CONTENTS Main Page Dynamic Development The Foundations of Developmental Biology Gametogenesis From Sperm and Egg to Embryo Genetic Regulation of Development Organizing the Multicellular Embryo Generating Cell Diversity Dynamic Development at a Glance

Development of the Mouse The mouse embryo is the embryo of choice for the study of mammalian development. Not only has the embryology of the mouse been studied extensively, but mouse genetics and genetic manipulation are readily conducted. One of the most powerful techniques for the study of mouse development is targeted mutagenesis, or the gene knockout.  One of the first steps in a gene knockout experiment is the insertion of stem cells into a mouse blastocyst. The stem cells containing the knocked out gene will be integrated into the the developing embryo.  This movie is a sampler from an educational video prepared by Cogito, demonstrating the microinjection of stem cells into a mouse blastula. Magnetic resonance microscopy has been used to obtain images of mouse embryos.  Study this informative link.   Movie:  Growth.mov Examine the movie of progressive stages of mouse development from 9 days gestation to birth. Stop the movie at a stage comparable to that of a 10-mm pig embryo and identify as many structures as possible. Also, examine carefully the formation and development of the appendages during development.

Dynamic Development at a Glance Main Page Dynamic Development

Dynamic Development is a Virtual Embryo learning resource.

This material may be reproduced for educational purposes only provided credit is given to the original source. Leon Browder & Laurie Iten (Ed.) Dynamic Development Last revised Wednesday, July 29, 1998