Cryobiology - A Short Course

Ken Muldrew, Dept. of Physiology & Biophysics, and Dept. of Surgery,
University of Calgary, Alberta, Canada.

Locksley E. McGann, Dept. of Pathology,
University of Alberta, Alberta, Canada.

This web-based textbook is intended as an introduction to the science of cryobiology-- the study of living things at low temperatures. It is a work in progress and will be built up piecemeal, as time permits. You may find various sections assume wildly different backgrounds for the reader, but hopefully as work progresses, this will become less of a problem.

Note: You will need IBM's techexplorer plugin to view the equations in this document as they are formatted in TeX. Go to IBM's site to get it.

Note to mountaineers: click here


1. Life at Low Temperatures

2. Historical Overview

3. Water

4. Aqueous Solutions

5. Permeability

6. Physical Aspects of Freezing

7. Freezing of Cells

8. Cryopreservation of Cells

9. Cryopreservation of Tissues and Organs

10. Cryosurgery

11. Hypothermia and Frostbite

12. Strategies for Survival in Cold Climates

13. Food Preservation by Freezing

14. Freezing Technology

15. Cryonics

WWW Resources for Cryobiology
Glossary of Unusual Terms
A Lexicon of Snow
Document last updated Mar. 25, 1999.
Copyright © 1997, Ken Muldrew.