Freezing of Cells
Investigations into Cryoinjury
In this chapter, we will review some of the classic papers in the field of
cryobiology to gain some insight into the current theories of
cryoinjury, the experimental basis for those ideas, and the concepts
that have been used to develop our modern (but far from complete)
understanding of the various phenomena associated with cryobiology. The
student should not take these brief notes as a substitute for
critically reading each of these papers, nor should she consider this
list as giving a complete survey of the field. Some of these papers have
been chosen merely to expose students from a particular background to a
way of thinking, or a literature, that they might otherwise have not
experienced. Others are classics in the field by all accounts. This list
is a starting point. There are many excellent papers that express
fundamental ideas that are not included. Perhaps with time the list will
grow more complete.
Hypotheses of the Mechanisms of Injury During Freezing and Thawing
Investigations into the Mechanism of Intracellular Freezing Injury
Document last updated Nov. 26, 1998.
Copyright © 1998, Ken Muldrew.