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Most
graduate training for the Department of Neuroscience is centered
in a complex of 4 contiguous buildings, with two new buildings nearing completion of construction.
The Health Science and Heritage Medical Buildings are active centers
for basic science research, and the Seaman MRI Center and Foothills
Hospital more in the area of clinical research.
Two new buildings, the Health Research Innovation Center and the
Translational Research Wing, will significantly increase the capacity
for both basic and clinical research and will house many neuroscience research labs.
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Health Research Innovation Center
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Foothills
Hospital
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Seaman MRI Centre
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Calgary has a defined
strength in the area of electrophysiology and biophysics. The majority
of basic science labs use single or dual patch clamp recordings of
in vitro tissue slices or ion channels expressed in heterologous cell
lines. Researchers have further access to Ca2+ imaging, laser photolysis,
and in vivo human and animal recordings. |
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The Microscopy and Imaging facility provides access to new Transmission
and Scanning Electron microscopes, an Atomic Force Microscope, and
a Confocal Deconvolution microscope, along with a full array of histology
equipment for preparing frozen or fixed tissues. Data analysis includes
extensive use of 3-D and 4-D image reconstruction, with expert staff
to assist in specimen preparation and imaging. |
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Members of the Department of Neuroscience have access to a group Olympus
Confocal imaging system that can be mounted on an upright or inverted
microscope. Both microscopes are equipped with a full suite of lenses
and differential interference contrast optics, with three laser lines
available for activation of fluorophores. |
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Magnetic
Resonance Imaging
Efforts
are focused on advancing magnetic resonance imaging techniques in
both basic sciences and clinical medicine. Medical physics, biomedical
engineering, computer science, mathematics and other technical discplines
play a role in the centre's ablity to understand and detect disease
and develop and deliver novel treatments to a wide range of patients.
The facility includes two MR research systems:
1.5 intra-operative magnet
3.0 T magnet
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Our behavioural testing facilities on main campus and the Health Science Centre are equipped with a wide array of apparatus' that can be used to assess sensory, motor and cognitive performance in mice and rats. These tests are used to understand the relationship between structure and function in the normal brain, as well as to evaluate the consequences of brain injury in animal models of human disorders including stroke, epilepsy, and Alzheimer, Huntington's and Parkinson's Diseases.
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research in health and pathology
stroke
DBS
MS
clinical trials
newly developed surgical robotics
spinal cord trauma and regeneration
auditory dysfunction
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