SARS-CoV-2 Spike protein (S) gene S:p.H69_V70del;Y144del;Y145del;N501Y;A570D;D614G;P681H literature reference collection
Antibody epitope effects
- B.1.1.7 variant constellation ablates Class 3 N-terminal domain targeting antibody COV2-2489.
(Chen et al. (2021))
Vaccine neutralization efficacy
- The neutralizing activity of vaccine was somewhat lower against B.1.1.7 in sera tested from most of the 24 patients with the BNT162b2 mRNA vaccine. (Fig. 4) (Chen et al. (2021))
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