Immunosuppression variant emergence
- Appeared (day 75) and persisted in chronic (152 day) SARS-CoV-2 infection of immunocompromised patient with severe antiphospholipid syndrome.
Appeared at same time as T478K,S494P but listed separately due to distance and different domains affected in the Spike (i.e. putatively an independent mutation from a functional standpoint since the former are from S1, the latter from S2).
(Choi et al. (2020))
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