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Alex Kim,  
BSc Neuroscience
University of Calgary, 2014
Hotchkiss Brain Institute
Health Research Innovation Center (HRIC) 1B42A
University of Calgary
Calgary Alberta Canada
T2N 4N1
Phone: 403-220-8451
FAX: 403-210-7446
abkim@ucalgary.ca

Training
BSc Neuroscience 2014
University of Calgary
Calgary Alberta



Awards
BSc
Dean’s List Faculty of Science 2011, 2012
Excellence in Biological Science Research, Undergraduate Research Symposium, 2011, 2012
Alberta Innovates - Health Solutions Summer Studentship 2012, 2013



Research Focus: KCa3.1 channel function in central neurons
Approach: I use patch clamp recordings in vitro to determine the physiological properties and functional roles for IKCa channels in central neurons
Preparations: In vitro slice preparation, voltage clamp, neurophysiology
Below are short summaries of my projects published from the lab.
Charybdotoxin slows the rate or repolarization of the parallel fiber-evoked EPSP A Cav3-IKCa interaction modulates cell excitability
   A recent study revealed that the intermediate conductance KCa channel (KCa3.1) is expressed in Purkinje cells and is linked to Cav3.2 T-type calcium channels, allowing KCa3.1 to be activated during the parallel fiber EPSP and generate an AHP that suppresses temporal summation of low frequency EPSPs (see Engbers et al. (2012)). My work involves extending this study to examine the extent to which KCa3.1 channels modulate excitability in other central neurons.

Abstracts

McLaughlin, R. J., Lee, T., Kim, A., and Hill, M. N. Corticotrophin hormone signaling regulates endocannabinoid signaling in the amygdala and prefrontal cortex. Society for Neuroscience, 2012.

Kim A. B., Gray J. M., Hermanson D., McLaughlin R. J., Wilson C. D., Vecchiarelli H. A., McEwen B. S., Schulkin J., Karatsoreos I. N., Patel S., and Hill M. N. Corticotropin releasing hormone enhances 2-Arachidonoylglycerol levels in the medial prefrontal Cortex. Society for Neuroscience 2014.

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